Erich Sackmann to give a tutorial on the Cell Membranes, Adhesion and Locomotion

May 16, 2018

1100 Lecture 1: The shell-string (tensegrity) model of cells
 The composite cell envelope
 Self-stabilization of cells by actin-microtubule cross talk
 A short look at the classical thermodynamic-elastic concept
 of membrane sculpturing
 An example: Lipid-protein sorting by the concept of
 hydrophobic matching.
 Adhesion domains as generators of solitary actin gelation

 1145 Coffee break
 1200 Lecture 2: Cell adhesion and locomotion
 Logistically controlled generation of functional membrane
 A paradigm: bi-stable molecular switches (Rac and Rho)
 The ubiquitous role of phosphoinositide lipid anchors
 PI(4,5)P2 P(3,4,5)P3.
 Hormone-induced self-organization of functional
 membrane machines
 Control of dendritic outgrowths: A new role for
 MARCKS proteins